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Materials that are less soluble in the liquid will increase the result faster than the material with greater solubility.The purpose of this module is to provide a better understanding on its separation and measurement techniques and its application. This inert gas goes through a glass column packed with silica that is coated with a liquid.
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The vaporized samples that are injected are then carried by an inert gas, which is often used by helium or nitrogen. To separate the compounds in gas-liquid chromatography, a solution sample that contains organic compounds of interest is injected into the sample port where it will be vaporized. A typical gas chromatograph consists of an injection port, a column, carrier gas flow control equipment, ovens and heaters for maintaining temperatures of the injection port and the column, an integrator chart recorder and a detector. The combination of gas chromatography and mass spectrometry is an invaluable tool in the identification of molecules. Among the various types of gas chromatography, gas-liquid chromatography is the method most commonly used to separate organic compounds. In organic chemistry, liquid-solid column chromatography is often used to separate organic compounds in solution. In early 1900s, Gas chromatography (GC) was discovered by Mikhail Semenovich Tsvett as a separation technique to separate compounds.